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Epalrestat
Synonym: 3-thiazolidineaceticacid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo; 5-((1z, 2e)-2-methyl-3-phenylpropenylidene)-4-oxo-2-thioxo-3-thiazolidineacet; E)-(e; EPALRESTAT; (e, e)-2-[5-(2-methyl-3-phenyl-prop-2-enylidene)-4-oxo-2-sulfanylidene-thiazo lidin-3-yl]acetic acid; AKOS BBS-00007767; OTAVA-BB BB7211260020; EPALRESTAT(KINEDAK)
CAS: 82159-09-9
MF: C15H13NO3S2
MW: C15H13NO3S2
Assay: 99%
uses
epalrestat is an aldose reductase inhibitor.
"long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, particularly in subjects with good glycemic control and limited microangiopathy."