Product Description
[English Name]Diclofenac sodium
[Test Method]HPLC
[Purity]≥99%
[Synonyms] Neriodin
[CAS No.]15307-79-6
[Mol. Formula]C14H10Cl2NNaO2
[Mol. Weight]318.14
[Purity]> 99% by HPLC
[Packaging] 25 KG/Drum
Package and quantity according to customer's detail requirement
[Remark] In stock, customized for large scale.
Description
Diclofenac (sold under a number of trade names) is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. It is supplied as or contained in medications under a variety of trade names.
The name "diclofenac" derives from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid. Diclofenac was first synthesized by Alfred Sallmann and Rudolf Pfister and introduced as Voltaren by Ciba-Geigy (now Novartis) in 1973.
In the United Kingdom, United States, India, and Brazil diclofenac may be supplied as either the sodium or potassium salt; in China, it is most often supplied as the sodium salt, while in some other countries it is only available as the potassium salt. It is available as a generic drug in a number of formulations, including diclofenac diethylamine, which is applied topically. Over-the-counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.
Applications
Acute and chronic rheumatoid arthritis, acute and chronic arthritis, acute and chronic ankylosing spondylitis, and osteoarthritis.
Periarthritis, bursitis, tendonitis and tenosynovitis.
Low back pain, sprains, strains and other soft tissue injuries.
Acute gout.
Dysmenorrhea or attachment inflammation, toothache and postoperative pain.
Post-traumatic pain and inflammation, such as sprains, muscle strains, etc.;
Severe otolaryngological infection pain and inflammation (such as tonsillitis, otitis, sinusitis, etc.) should be combined with anti-infective drugs.
Function
1.This product is a synthetic prostaglandin F2a homologue.
2.Strong the function of dissolving luteal; It can quickly cause corpus luteum regression, and suppress the secretion;
3. Have direct excitation effect on uterine smooth muscle; It can cause uterine smooth muscle contraction, cervical relaxation.
4.For sexual cycle normal animals, usually Estrus in 2 ~ 5 days after heat treatment.
Specifications
COA
Item | Specification | Result |
Appearance | A white or slightly yellowish crystalline powder | White crystalline powder |
Identification | A.IR B.HPLC C.test of sodium salt | Accord Accord Conform |
Appearance of Solution | 5.0% of methanol solution 440nm, nmt0.05 | 0.011 |
Melting point | 288-290℃ | Conform |
Clarity of solution | Equal to methanol | Pass |
PH | 6.5~7.5 | 7.2 |
Related substance | Individual impurity: 0.02%max Total inpurities:0.5%max | Individual impurity: 0.01%max total impurities: 0.4%max |
Chloride | ≤0.02% | ≤0.01% |
Heavy metal | 10ppm | 9ppm |
Assay(by HPLC) | ≥98.5% | ≥99.5% |
Assay | ≥98.0% | ≥99.0% |
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